Search on: PTEROYLPOLYGLUTAMIC ACIDS 
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Descriptor English:   Pteroylpolyglutamic Acids 
Descriptor Spanish:   Ácidos Pteroilpoliglutámicos 
Descriptor Portuguese:   Ácidos Pteroilpoliglutâmicos 
Synonyms English:   Pteroylpolyglutamates
Acids, Pteroylpolyglutamic
Folates, Polyglutamate
Polyglutamates, Folate
Folate Polyglutamates
Polyglutamate Folates  
Tree Number:   D03.633.100.733.631.400.600
Definition English:   Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays. 
Indexing Annotation English:   deficiency: coordinate PTEROYLPOLYGLUTAMIC ACIDS /defic (IM) with FOLIC ACID DEFICIENCY (IM)
Pharmacological Action:   Vitamin B Complex
 
History Note English:   91(79); was see under FOLIC ACID 1979-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   27777 
Unique Identifier:   D011624 

Occurrence in VHL:
 

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